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Devastating Turns and Shocking Decisions: General Hospital Spoilers for the Week of May 5, 2025

Port Charles is on the verge of chaos as the week of May 5, 2025, promises life-changing decisions, explosive confrontations, and dangerous cover-ups. In the latest General Hospital spoilers, Brad Cooper is at the center of a pivotal storyline that could permanently alter his future, while familiar faces find themselves entangled in secrets, betrayal, and moral dilemmas.

Brad Cooper Makes a Game-Changing Move

In one of the most highly anticipated moments of the week, Brad Cooper (Perry Shen) makes a bold move that could shift the landscape of Port Charles. In Monday’s preview, Brad is seen entering Dr. Portia Robinson’s office at the hospital with a determined tone, declaring that he’s “there to collect.” What he’s collecting and what leverage he holds remains a mystery—but it’s clearly enough to leave Portia shaken.

Portia (Brook Kerr), who is already under immense pressure, may find herself with yet another complication—especially with the lingering fallout from Drew Cain’s drugging scandal.

Drew Cain Fights to Clear His Name

Speaking of Drew Cain (Cameron Mathison), he’s a man on a mission. Determined to prove that he was drugged with Ketamine, Drew is hell-bent on protecting not only his political aspirations but also his integrity in the eyes of Willow Tate Corinthos (Katelyn MacMullen). Drew knows he didn’t collapse out of weakness—he was sabotaged. And he wants justice.

Fans already know that Jinda Paige Herschel was recruited by Portia and Nina Reeves (Cynthia Watros) to drug Drew. Although Jinda plans to disappear to Australia, Drew may have a secret weapon that could draw her back to Port Charles—and into the line of fire.

Willow’s Crisis of Faith in Drew

In a deeply emotional preview, Willow opens up to her mother, Nina, wondering aloud if she’s foolish for trusting Drew. Her question—”Am I an idiot for believing him?”—shows just how torn she is between her loyalty to Drew and the growing pressure from outside forces. Nina may be hiding her own guilt in the matter, further complicating their fragile mother-daughter bond.

The Widening Investigation

Drew doesn’t wait for justice to fall into his lap. He notifies Mac Scorpio (John J. York) that a crime has been committed, setting off a wave of questioning and suspicion. As the investigation heats up, viewers are left to wonder: will Portia and Nina’s silence end up framing an innocent party? The stakes have never been higher.

Rocco’s Spiral and Cody’s Discovery

Meanwhile, danger looms in the form of a personal crisis for Rocco Falconeri (Finn Carr), who reportedly gets drunk and passes out—an alarming development that could have devastating consequences. It’s Cody Bell (Josh Kelly) who may find him in this vulnerable state, potentially altering Cody’s own arc as he becomes more entangled in the Falconeri family’s troubles.

Later, Rocco expresses remorse, and the fallout from his actions could ripple through multiple families.

Tough Love and Guilt

Elsewhere in Port Charles, Jason Morgan (Steve Burton) offers some stern, much-needed guidance to his son Danny Morgan (Asher Antonisen), reinforcing the show’s generational themes of legacy and accountability.

Josslyn Jacks (Eden McCoy) continues to wrestle with guilt after sabotaging Emma Scorpio-Drake’s academic project. Although she may have had justifiable motives, the emotional weight of her actions is taking a toll. Fortunately, her confidante Vaughn (Bryce Turey) reminds her that some sacrifices are made for the greater good—a message that might offer temporary solace.

Lulu, Brook Lynn, and Dante Are Pulled into the Drama

The week also brings major developments for General Hospital’s supporting power players. Liesl Obrecht (Reena Sofer) issues a desperate plea to Dante Falconeri (Dominic Zamprogna), setting off speculation about a looming crisis.

Midweek, Brook Lynn Quartermaine (Amanda Setton) is left baffled by unexpected news. By Friday, she and Harrison Chase (Josh Swickard) meet with Alexis Davis (Nancy Lee Grahn) for a significant discussion, which could have major legal or family implications.

Meanwhile, Lulu Spencer (Emme Rylan) starts asking hard questions of Ned Quartermaine (Wally Kurth), and Kristina Corinthos-Davis (Kate Mansi) opens her heart to Lucky Spencer (Jonathan Jackson) in a surprisingly vulnerable moment.

Sasha vs. Willow — Again

As the week winds down, tensions between Sasha Gilmore (Sofia Mattsson) and Willow erupt once more. These two women have clashed before, but this time, the stakes—and emotions—are even higher. Whether they can find common ground or further implode remains to be seen.

Sidwell’s Mysterious New Proposition

Finally, shady player Jen Sidwell (Carlo Rota) returns with yet another proposition. While details remain vague, his schemes are never simple, and his presence usually signals bad news for someone.


Which storyline are you most excited to see unfold during the week of May 5, 2025? Will Drew get justice? Can Willow and Nina recover from the truth? Is Brad finally taking control of his destiny? Share your thoughts in the comments, and keep watching General Hospital on ABC for more drama, emotion, and unforgettable twists.

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